Ecotox Centers are offering consultation services focused on REACH legislation, Management of SVHC substances, communication in supply chain and support for EU chemicals legislation compliance.
We do have done several projects in terms of:
- REACH Authorisation applications – development of whole REACH Authorisation documentation.
- Downstream users compliance – Internal Documentation for REACH Authorisation Compliance (IDRAC).
If you have questions please contact us:
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https://echa.europa.eu/authorisation-list
| # | Substance name | Intrinsic property(ies) referred to in Article 57 | Latest application date | Sunset date |
| 1 | 5-tert-butyl-2,4,6-trinitro-m-xylene (Musk xylene)
EC No: 201-329-4 CAS No: 81-15-2 |
vPvB | 21/02/2013 | 21/08/2014 |
| 2 | 4,4’- Diaminodiphenylmethane (MDA)
EC No: 202-974-4 CAS No: 101-77-9 |
Carcinogenic | 21/02/2013 | 21/08/2014 |
| 3 | Hexabromocyclododecane (HBCDD)
and all major diastereoisomers identified |
PBT | 21/02/2014 | 21/08/2015 |
| 4 | Bis(2-ethylhexyl) phthalate (DEHP)
EC No: 204-211-0 CAS No: 117-81-7 |
Toxic for reproduction | 21/08/2013 | 21/02/2015 |
| 5 | Benzyl butyl phthalate (BBP)
EC No: 201-622-7 CAS No: 85-68-7 |
Toxic for reproduction | 21/08/2013 | 21/02/2015 |
| 6 | Dibutyl phthalate (DBP)
EC No: 201-557-4 CAS No: 84-74-2 |
Toxic for reproduction | 21/08/2013 | 21/02/2015 |
| 7 | Diisobutyl phthalate (DIBP)
EC No: 201-553-2 CAS No: 84-69-5 |
Toxic for reproduction | 21/08/2013 | 21/02/2015 |
| 8 | Diarsenic trioxide
EC No: 215-481-4 CAS No: 1327-53-3 |
Carcinogenic | 21/11/2013 | 21/05/2015 |
| 9 | Diarsenic pentaoxide
EC No: 215-116-9 CAS No: 1303-28-2 |
Carcinogenic | 21/11/2013 | 21/05/2015 |
| 10 | Lead chromate
EC No: 231-846-0 CAS No: 7758-97-6 |
Carcinogenic
Toxic for reproduction |
21/11/2013 | 21/05/2015 |
| 11 | Lead sulfochromate yellow
EC No: 215-693-7 CAS No: 1344-37-2 |
Carcinogenic
Toxic for reproduction |
21/11/2013 | 21/05/2015 |
| 12 | Lead chromate molybdate sulfate red
EC No: 235-759-9 CAS No: 12656-85-8 |
Carcinogenic
Toxic for reproduction |
21/11/2013 | 21/05/2015 |
| 13 | Tris(2-chloroethyl) phosphate
EC No: 204-118-5 CAS No: 115-96-8 |
Toxic for reproduction | 21/02/2014 | 21/08/2015 |
| 14 | 2,4-dinitrotoluene (2,4-DNT)
EC No: 204-450-0 CAS No: 121-14-2 |
Carcinogenic | 21/02/2014 | 21/08/2015 |
| 15 | Trichloroethylene
EC No: 201-167-4 CAS No: 79-01-6 |
Carcinogenic | 21/10/2014 | 21/04/2016 |
| 16 | Chromium trioxide
EC No: 215-607-8 CAS No: 1333-82-0 |
Carcinogenic
Mutagenic |
21/03/2016 | 21/09/2017 |
| 17 | Acids generated from chromium trioxide and their oligomers | Carcinogenic | 21/03/2016 | 21/09/2017 |
| 18 | Sodium dichromate
EC No: 234-190-3 CAS No: 10588-01-9, 7789-12-0 |
Carcinogenic
Mutagenic Toxic for reproduction |
21/03/2016 | 21/09/2017 |
| 19 | Potassium dichromate
EC No: 231-906-6 CAS No: 7778-50-9 |
Carcinogenic
Mutagenic Toxic for reproduction |
21/03/2016 | 21/09/2017 |
| 20 | Ammonium dichromate
EC No: 232-143-1 CAS No: 7789-09-5 |
Carcinogenic
Mutagenic Toxic for reproduction |
21/03/2016 | 21/09/2017 |
| 21 | Potassium chromate
EC No: 232-140-5 CAS No: 7789-00-6 |
Carcinogenic
Mutagenic |
21/03/2016 | 21/09/2017 |
| 22 | Sodium chromate
EC No: 231-889-5 CAS No: 7775-11-3 |
Carcinogenic
Mutagenic Toxic for reproduction |
21/03/2016 | 21/09/2017 |
| 23 | Formaldehyde, oligomeric reaction products with aniline
EC No: 500-036-1 CAS No: 25214-70-4 |
Carcinogenic | 22/02/2016 | 22/08/2017 |
| 24 | Arsenic acid
EC No: 231-901-9 CAS No: 7778-39-4 |
Carcinogenic | 22/02/2016 | 22/08/2017 |
| 25 | Bis(2-methoxyethyl) ether
EC No: 203-924-4 CAS No: 111-96-6 |
Toxic for reproduction | 22/02/2016 | 22/08/2017 |
| 26 | 1,2-dichloroethane (EDC)
EC No: 203-458-1 CAS No: 107-06-2 |
Carcinogenic | 22/05/2016 | 22/11/2017 |
| 27 | 2,2′-dichloro-4,4′-methylenedianiline (MOCA)
EC No: 202-918-9 CAS No: 101-14-4 |
Carcinogenic | 22/05/2016 | 22/11/2017 |
| 28 | Dichromium tris(chromate)
EC No: 246-356-2 CAS No: 24613-89-6 |
Carcinogenic | 22/07/2017 | 22/01/2019 |
| 29 | Strontium chromate
EC No: 232-142-6 CAS No: 7789-06-2 |
Carcinogenic | 22/07/2017 | 22/01/2019 |
| 30 | Potassium hydroxyoctaoxodizincatedichromate
EC No: 234-329-8 CAS No: 11103-86-9 |
Carcinogenic | 22/07/2017 | 22/01/2019 |
| 31 | Pentazinc chromate octahydroxide
EC No: 256-418-0 CAS No: 49663-84-5 |
Carcinogenic | 22/07/2017 | 22/01/2019 |
| 32 | 1-bromopropane (n-propyl bromide)
EC No: 203-445-0 CAS No: 106-94-5 |
Toxic for reproduction | 04/01/2019 | 04/07/2020 |
| 33 | Diisopentyl phthalate
EC No: 210-088-4 CAS No: 605-50-5 |
Toxic for reproduction | 04/01/2019 | 04/07/2020 |
| 34 | 1,2-Benzenedicarboxylic acid, di-C6-8-branched alkyl esters, C7-rich
EC No: 276-158-1 CAS No: 71888-89-6 |
Toxic for reproduction | 04/01/2019 | 04/07/2020 |
| 35 | 1,2-Benzenedicarboxylic acid, di-C7-11-branched and linear alkyl esters
EC No: 271-084-6 CAS No: 68515-42-4 |
Toxic for reproduction | 04/01/2019 | 04/07/2020 |
| 36 | 1,2-Benzenedicarboxylic acid, dipentyl ester, branched and linear
EC No: 284-032-2 CAS No: 84777-06-0 |
Toxic for reproduction | 04/01/2019 | 04/07/2020 |
| 37 | Bis(2-methoxyethyl) phthalate
EC No: 204-212-6 CAS No: 117-82-8 |
Toxic for reproduction | 04/01/2019 | 04/07/2020 |
| 38 | Dipentyl phthalate
EC No: 205-017-9 CAS No: 131-18-0 |
Toxic for reproduction | 04/01/2019 | 04/07/2020 |
| 39 | n-pentyl-isopentylphthalate
EC No: 933-378-9 CAS No: – |
Toxic for reproduction | 04/01/2019 | 04/07/2020 |
| 40 | Anthracene oil
A complex combination of polycyclic aromatic hydrocarbons obtained from coal tar having an approximate distillation range of 300°C to 400°C (572°F to 752°F). Composed primarily of phenanthrene, anthracene and carbazole. EC No: 292-602-7 CAS No: 90640-80-5 |
Carcinogenic
PBT vPvB |
04/04/2019 | 04/10/2020 |
| 41 | Pitch, coal tar, high-temp.
The residue from the distillation of high temperature coal tar. A black solid with an approximate softening point from 30°C to 180°C (86°F to 356°F). Composed primarily of a complex mixture of three or more membered condensed ring aromatic hydrocarbons. EC No: 266-028-2 CAS No: 65996-93-2 |
Carcinogenic
PBT vPvB |
04/04/2019 | 04/10/2020 |
| 42 | 4-(1,1,3,3-tetramethylbutyl)phenol, ethoxylated
covering well-defined substances and UVCB substances, polymers and homologues |
Endocrine disrupting properties | 04/07/2019 | 04/01/2021 |
| 43 | 4-Nonylphenol, branched and linear, ethoxylated
substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, ethoxylated covering UVCB- and well-defined substances, polymers and homologues, which include any of the individual isomers and/or combinations thereof |
Endocrine disrupting properties | 04/07/2019 | 04/01/2021 |
| 44 | 1,2-Benzenedicarboxylic acid, dihexyl ester, branched and linear
EC No: 271-093-5 CAS No: 68515-50-4 |
Toxic for reproduction (category 1B) | 27 August 2021 | 27 February 2023 |
| 45 | Dihexyl phthalate
EC No: 201-559-5 CAS No: 84-75-3 |
Toxic for reproduction (category 1B) | 27 August 2021 | 27 February 2023 |
| 46 | 1,2-benzenedicarboxylic acid, di-C6-10-alkyl esters; 1,2-benzenedicarboxylic acid, mixed decyl and hexyl and octyl diesters with ≥ 0,3 % of dihexyl phthalate
(EC No 201-559-5) EC No: 271-094-0; 272-013-1 CAS No: 68515-51-5; 68648-93-1 |
Toxic for reproduction (category 1B) | 27 August 2021 | 27 February 2023 |
| 47 | Trixylyl phosphate
EC No: 246-677-8 CAS No: 25155-23-1 |
Toxic for reproduction (category 1B) | 27 November 2021 | 27 May 2023 |
| 48 | Sodium perborate; perboric acid, sodium salt
EC No: 239-172-9; 234-390-0 CAS No: – |
Toxic for reproduction (category 1B) | 27 November 2021 | 27 May 2023 |
| 49 | Sodium peroxometaborate
EC No: 231-556-4 CAS No: 7632-04-4 |
Toxic for reproduction (category 1B) | 27 November 2021 | 27 May 2023 |
| 50 | 5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1- yl)-5-methyl-1,3-dioxane [1], 5-sec-butyl-2- (4,6-dimethylcyclohex-3-en-1-yl)-5-methyl- 1,3-dioxane [2] [covering any of the individual stereoisomers of [1] and [2] or any combination thereof]
EC No: – CAS No: – |
vPvB | 27 February 2022 | 27 August 2023 |
| 51 | 2-(2H-benzotriazol-2-yl)-4,6-ditertpentylphenol (UV-328)
EC No: 247-384-8 CAS No: 25973-55-1 |
PBT, vPvB | 27 May 2022 | 27 November 2023 |
| 52 | 2,4-di-tert-butyl-6-(5-chlorobenzotriazol-2- yl)phenol (UV-327)
EC No: 223-383-8 CAS No: 3864-99-1 |
vPvB | 27 May 2022 | 27 November 2023 |
| 53 | 2-(2H-benzotriazol-2-yl)-4-(tert-butyl)-6- (sec-butyl)phenol (UV-350) EC No: 253-037-1
CAS No: 36437-37-3 |
vPvB | 27 May 2022 | 27 November 2023 |
| 54 | 2-benzotriazol-2-yl-4,6-di-tert-butylphenol (UV-320) EC No: 223-346-6 CAS No: 3846-71-7 | PBT, vPvB | 27 May 2022 | 27 November 2023 |
EKOTOX CENTERS
Ekotoxikologické centrum CZ
Centrum Ekotoksykologiczne (PL)
Ekotoxikologické centrum Bratislava, s.r.o. (SK)
Tomášikova 10/F, 821 03 Bratislava
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Tel.: +421 (2) 4594 3712, 4594 5223
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